Here are five talking points from the weekend's action:
AC Milan grabbed a 1-1 draw at Manchester United in the blockbuster Europa League last-16 first-leg at Old Trafford on Thursday.
Pogba, who came through United's academy, left the club for free in 2012 after Ferguson fell out with the Frenchman's agent Mino Raiola but returned following a four-year spell at Juventus for a then-world record fee in 2016.
Manchester United's current malaise was laid bare as they struggled past third-tier Rochdale 5-3 on penalties after a 1-1 draw in the League Cup third round.
Manchester United remain winless at home in the league this season after Arsenal enjoyed their first win at Old Trafford
Images from the English Premier League matches played on Saturday.
English Premier League champions Manchester City cruised to a 2-0 win over struggling Manchester United in their derby at Old Trafford on Saturday.
'Pure, unadulterated football joy has been in short supply for United fans for a long time now,' complains Dhruv Munjal.
Manchester United suffered their first defeat under interim manager Ralf Rangnick, falling to a 1-0 loss at home to Wolverhampton Wanderers in the English Premier League on Monday.
Following is a match by match look at the English Premier League's weekend fixtures
Manchester United's Champions League qualification hopes suffered a blow after an equaliser deep in stoppage time from Michael Obafemi earned Southampton a 2-2 draw in the Premier League at Old Trafford on Monday.
Chilean forward Alex Sanchez returned to haunt his old club with the opening goal in Manchester United's 3-1 victory at Arsenal in a heavyweight FA Cup fourth-round clash.
After a tense encounter finished 1-1 following extra time, Villareal's Rulli stepped up after every on-field player scored their spot kicks and he comfortably beat Spaniard De Gea
Manchester City stumbled to the most unexpected defeat of the Premier League season on Saturday before neighbours Manchester United began their brave new world under Ole Gunnar Solskjaer with a glorious reminder of long-forgotten attacking swagger.
Should Manchester United win their next two games, the gap will be cut to four points and while only a collapse of astonishing proportions would deny Manchester City the title.
Juergen Klopp's side, chasing their maiden title in the Premier League era and first in the top flight in 30 years, took a 14th-minute lead from a Virgil van Dijk header but had to wait until stoppage time to put the game to bed through Mohamed Salah.
The resumption of the German Bundesliga next weekend amid the COVID-19 crisis will give hope to other European leagues that they can also successfully return, according to Schalke 04 coach David Wagner.
Chelsea's 0-0 home draw with second-placed United ensured Thomas Tuchel is still undefeated in nine games since replacing Frank Lampard, but it meant they failed to dislodge fourth-placed West Ham United who became Manchester City's 20th successive victims in all competitions on Saturday.
Manchester City chalked up yet another victory to maintain their stranglehold of the Premier League title race but pursuers Manchester United and Leicester City both secured important wins to enhance their top-four bids on Sunday.
Manchester United were held 1-1 at Wolverhampton Wanderers and missed out on taking top spot in the English Premier League.
News of all that's transpired on and off the football field
Tottenham Hotspur routed Bournemouth 5-0 as they leapfrogged City into second place in the league, six points behind leaders Liverpool who thrashed Newcastle United 4-0.
IMAGES from the Europa League semifinal played between Manchester United and Sevilla in Cologne on Sunday.
Chelsea, Manchester City and Manchester United enjoyed comfortable wins in the English Premier League on Saturday as fans returned to stadiums after an eight-month absence.
As Manchester City fans left Goodison Park after a 2-0 victory over Everton on Wednesday that sent their team back to the top of the Premier League, they aimed their chants across adjacent Stanley Park to title rivals Liverpool.
Bayern Munich wasted a two-goal lead and needed a lucky 82nd- minute winner from Joshua Kimmich to beat Borussia Dortmund 3-2 in Germany's Super Cup on Wednesday and secure their fifth title of the year.
Roma teenager Afena-Gyan plays down apparent racist remark.
Manchester United kept up their chase for a Champions League qualification spot with Marcus Rashford and Anthony Martial on target in a 2-0 Premier League win over Crystal Palace, while Leicester secured a 2-0 home win over Sheffield United.
Liverpool raised the bar so high and enjoyed such a huge winning margin in claiming the English Premier League title last season it would be churlish to doubt their credentials for a repeat showing.
Timo Werner scored his first goal of the season as a much-changed Chelsea side crept into the fourth round of the League Cup by beating Aston Villa 4-3 on penalties after the Stamford Bridge clash ended 1-1 on Wednesday.
Leicester City reached the FA Cup final for the first time in more than 50 years
Spaniard Herrera finished off a fine move with a precise header from Pogba's cross just past the half-hour and United's French midfielder scored himself when he nodded powerfully home from a Marcus Rashford delivery before the break.
Liverpool's bandwagon rolled on as they crushed Merseyside rivals Everton 5-2
News of all that's transpired on and off the football field.
Ole Gunnar Solskjaer's side, who had won their last ten away games in the Premier League, stay third on 27 points, a point behind second-placed Leicester.
Manchester City lost 1-0 to Manchester United on Wednesday but hung on to reach the League Cup final 3-2 on aggregate and will face Aston Villa at Wembley. Nemanja Matic's 35th-minute strike gave United victory at the Etihad Stadium but the midfielder was later sent off and it was not enough to overturn the 3-1 deficit from the semi-final first leg at Old Trafford.
A preview of the line-up action in the English Premier League.
United looked more solid after the introduction of midfielder Nemanja Matic at the break and got a foothold in the tie through a 70th-minute goal from Marcus Rashford.
City were given a stern test on a wet and windy night at a noisy Kassam Stadium but two goals from Raheem Sterling eventually saw them through.
Images from Thursday's action in the Europa League Europa League - Round of 16 Second Leg - matches.